PUBLICATIONS | NANOMEDICINE

Dexamethasone-loaded H2O2-activatable anti-inflammatory nanoparticles for on-demand therapy of inflammatory respiratory diseases.

Lee, H., Jeong, S. W., Jung, E., & Lee, D. (2020).Dexamethasone-loaded H2O2-activatable anti-inflammatory nanoparticles for on-demand therapy of inflammatory respiratory diseases. Nanomedicine: Nanotechnology, Biology and Medicine, 30, 102301.

Thrombus targeting aspirin particles for near infrared imaging and on-demand therapy of thrombotic vascular diseases

Lee, J., Jeong, L., Jung, E., Ko, C., Seon, S., Noh, J., & Lee, D. (2019). Thrombus targeting aspirin particles for near infrared imaging and on-demand therapy of thrombotic vascular diseases. Journal of Controlled Release, 304, 164-172.

Engineered Polymeric Micelles for Combinational Oxidation Anticancer Therapy through Concurrent HO-1 Inhibition and ROS Generation

Noh, J., Jung, E., Lee, J., Hyun, H., Hong, S., & Lee, D. (2019). Engineered polymeric micelles for combinational oxidation anticancer therapy through concurrent HO-1 inhibition and ROS generation. Biomacromolecules, 20(2), 1109-1117.

Stimulus-activatable echogenic maltodextrin nanoparticles as nanotheranostic agents for peripheral arterial disease

Jung, E., Lee, J., Jeong, L., Park, S., Lee, M., Song, C., & Lee, D. (2019). Stimulus-activatable echogenic maltodextrin nanoparticles as nanotheranostic agents for peripheral arterial disease. Biomaterials, 192, 282-291.

Ultrasound imaging and on-demand therapy of peripheral arterial diseases using H2O2-Activated bubble generating anti-inflammatory polymer particles

Jung, E., Noh, J., Kang, C., Yoo, D., Song, C., & Lee, D. (2018). Ultrasound imaging and on-demand therapy of peripheral arterial diseases using H2O2-Activated bubble generating anti-inflammatory polymer particles. Biomaterials, 179, 175-185.

Acid-triggered echogenic nanoparticles for contrast-enhanced ultrasound imaging and therapy of acute liver failure

Go, Y., Lee, H., Jeong, L., Sun, S., Hong, E., Jung, E., ... & Song, C. (2018). Acid-triggered echogenic nanoparticles for contrast-enhanced ultrasound imaging and therapy of acute liver failure. Biomaterials, 186, 22-30.

Dual Imaging-Guided Oxidative–Photothermal Combination Anticancer Therapeutics

Noh, J., Jung, E., Yoo, D., Kang, C., Kim, C., Park, S., ... & Lee, D. (2018). Dual Imaging-Guided Oxidative–Photothermal Combination Anticancer Therapeutics. ACS applied materials & interfaces, 10(47), 40424-40433.

Acid-activatable oxidative stress-inducing polysaccharide nanoparticles for anticancer therapy

Yoo, W.; Yoo, D.; Hong, E.; Jung, E.; Go, Y.; Singh, S. V. B.; Khang, G.; Lee, D., J Control Release 2018, 269, 235-244.

Molecularly Engineered Theranostic Nanoparticles for Thrombosed Vessels: H2O2-Activatable Contrast-Enhanced Photoacoustic Imaging and Antithrombotic Therapy

Jung, E.; Kang, C.; Lee, J.; Yoo, D.; Hwang, D. W.; Kim, D.; Park, S. C.; Lim, S. K.; Song, C.; Lee, D., ACS Nano 2018.

Oligochitosan-stabilized photoluminescent gold nanoconstructs for optical bioimaging

Yoo, D.; Lee, D., Biomater Res 2017, 21, 20.

Near infrared dye-conjugated oxidative stress amplifying polymer micelles for dual imaging and synergistic anticancer phototherapy

Yang, W.; Noh, J.; Park, H.; Gwon, S.; Swami Vetha, B. S.; Song, C.; Lee, D., 2017; Vol. 154.

Hydrogen peroxide-responsive engineered polyoxalate nanoparticles for enhanced wound healing

Swami Vetha, B. S.; Park, H.; Khang, G.; Lee, D., 2017.

Fibrin-Targeted and H2O2-Responsive Nanoparticles as a Theranostics for Thrombosed Vessels

Kang, C.; Gwon, S.; Song, C.; M Kang, P.; Park, S.-C.; Jeon, J.; Won Hwang, D.; Lee, D., 2017; Vol. 11.

Dual Stimuli-Activatable Oxidative Stress Amplifying Agent as a Hybrid Anticancer Prodrug
Han, E.; Kwon, B.; Yoo, D.; Kang, C.; Khang, G.; Lee, D.,. 2017; Vol. 28.

Neuropeptide Y 3-36 Incorporated Into PVAX Nanoparticle Improves Functional Blood Flow In A Murine Model Of Hind Limb Ischemia

Eshun, D.; Saraf, R.; Bae, S.; Jeganathan, J.; Mahmood, F.; Dilmen, S.; Ke, Q.; Lee, D.; M. Kang, P.; Matyal, R., 2017; Vol. 122, p jap.00467.2016.

H2O2-responsive antioxidant polymeric nanoparticles as therapeutic agents for peripheral arterial disease

Kwon, B.; Kang, C.; Kim, J.; Yoo, D.; Cho, B.-R.; M. Kang, P.; Lee, D., 2016; Vol. 511.

Nano-Fenton Reactors as a New Class of Oxidative Stress Amplifying Anticancer Therapeutic Agents

Kwon, B.; Han, E.; Yang, W.; Cho, W.; Yoo, W.; Yeon Hwang, J.; Kwon, B.-M.; Lee, D., 2016; Vol. 8.

H2O2-triggered bubble generating antioxidant polymeric nanoparticles as ischemia/reperfusion targeted nanotheranostics

Kang, C.; Cho, W.; Park, M.; Kim, J.; Park, S.; Shin, D.; Song, C.; Lee, D., 2016; Vol. 85.

Porous antioxidant polymer microparticles as therapeutic systems for the airway inflammatory diseases

Jeong, D.; Kang, C.; Jung, E.; Yoo, D.; Wu, D.; Lee, D., 2016; Vol. 233.

Amplification of oxidative stress by a dual stimuli-responsive hybrid drug enhances cancer cell death

Noh, J.; Kwon, B.; Han, E.; Park, M.; Yang, W.; Cho, W.; Yoo, W.; Khang, G.; Lee, D., 2015; Vol. 6, p 6907.

Hydrogen peroxide-activatable antioxidant prodrug as a targeted therapeutic agent for ischemia-reperfusion injury

Lee, D.; Park, S.; Bae, S.; Jeong, D.; Park, M.; Kang, C.; Yoo, W.; Samad, M.; Ke, Q.; Khang, G.; M Kang, P., 2015; Vol. 5, p 16592.

P-Hydroxybenzyl alcohol-containing biodegradable nanoparticle improves functional blood flow through angiogenesis in a mouse model of hindlimb ischemia

Cho, B.-R.; Ryeol Ryu, D.; Lee, K.-S.; Lee, D.-K.; Bae, S.; Goo Kang, D.; Ke, Q.; S. Singh, S.; Ha, K.-S.; Kwon, Y.; Lee, D.; M. Kang, P.; Misun, K., 2015; Vol. 53.

Therapeutic use of H2O2-responsive anti-oxidant polymer nanoparticles for doxorubicin-induced cardiomyopathy

Park, S.; Yoon, J. H.; Bae, S.; Park, M.; Kang, C.; Ke, Q.; Lee, D.; M Kang, P., 2014; Vol. 35.

Dual pH-sensitive oxidative stress generating micellar nanoparticles as a novel anticancer therapeutic agent

Park, S.; Kwon, B.; Yang, W.; Han, E.; Yoo, W.; Lee, D., 2014; Vol. 196.

Antioxidant polymeric prodrug microparticles as a therapeutic system for acute liver failure

Ko, E.; Jeong, D.; Kim, J.; Park, S.; Khang, G.; Lee, D., 2014; Vol. 35.

Antioxidant polymeric nanoparticles as novel therapeutics for airway inflammatory diseases

Yoo, D.; Guk, K.; Kim, H.; Khang, G.; Wu, D.; Lee, D., 2013; Vol. 450.

Ketal containing amphiphilic block copolymer micelles as pH-sensitive drug carriers

Lee, I.; Park, M.; Kim, Y.; Hwang, O.; Khang, G.; Lee, D., 2013; Vol. 448.

Hydrogen peroxide-responsive copolyoxalate nanoparticles for detection and therapy of ischemia-reperfusion injury

Lee, D.; Bae, S.; Ke, Q.; Lee, J.; Song, B.; Karumanchi, S. A.; Khang, G.; Choi, H. S.; Kang, P. M., J Control Release 2013, 172 (3), 1102-10.

Hydrogen peroxide-responsive copolyoxalate nanoparticles for detection and therapy of ischemia–reperfusion injury

Lee, D.; Bae, S.; Ke, Q.; Lee, J.; Song, B.; Ananth Karumanchi, S.; Khang, G.; Choi, H.; M Kang, P., 2013; Vol. 172.

H2O2-responsive molecularly engineered polymer nanoparticles as ischemia/reperfusion-targeted nanotherapeutic agents

Lee, D.; Bae, S.; Hong, D.; Lim, H.; Yoon, J. H.; Hwang, O.; Park, S.; Ke, Q.; Khang, G.; M Kang, P., 2013; Vol. 3, p 2233.

Inflammation-Responsive Antioxidant Nanoparticles Based on a Polymeric Prodrug of Vanillin

Kwon, J.; Kim, J.; Park, S.; Khang, G.; M Kang, P.; Lee, D., 2013; Vol. 14.

Dual Acid-Responsive Micelle-Forming Anticancer Polymers as New Anticancer Therapeutics

Kim, B.; Lee, E.; Kim, Y.; Park, S.; Khang, G.; Lee, D., 2013; Vol. 23.

Acid-cleavable ketal containing poly(β-amino ester) for enhanced siRNA delivery

Guk, K.; Lim, H.; Kim, B.; Hong, M.; Khang, G.; Lee, D., 013; Vol. 453.

Acid-Degradable Cationic Poly(ketal amidoamine) for Enhanced RNA Interference In Vitro and In Vivo

Lim, H.; Noh, J.; Kim, Y.; Kim, H.; Kim, J.; Khang, G.; Lee, D., 2012; Vol. 14.

Detection And Therapy Of Ischemia-reperfusion Injury Using Hydrogen Peroxide-responsive Molecularly Engineered Polymer Nanoparticles

Lee, D.; Bae, S.; Hong, D.; Hwang, O.; Park, S.; Yoon, J. H.; Ke, Q. G.; Kang, P. M., Circ Res 2012, 111 (12), E380-E381.

Fully biodegradable and cationic poly(amino oxalate) particles for the treatment of acetaminophen-induced acute liver failure

Kim, H.; Kim, Y.; Guk, K.; Yoo, D.; Lim, H.; Kang, G.; Lee, D., 2012; Vol. 434, p 243-50.

Imaging: Chemiluminescent and Antioxidant Micelles as Theranostic Agents for Hydrogen Peroxide Associated-Inflammatory Diseases

Cho, S.; Hwang, O.; Lee, I.; Lee, G.; Yoo, D.; Khang, G.; M. Kang, P.; Lee, D.,

Adv. Funct. Mater. 19/2012). 2012; Vol. 22.

Enhanced cytosolic drug delivery using fully biodegradable poly(amino oxalate) particles

Seong, K.; Seo, H.; Ahn, W.; Yoo, D.; Cho, S.; Khang, G.; Lee, D., 2011; Vol. 152, p 257-63.

Detection of Hydrogen Peroxide in vitro and in vivo Using Peroxalate Detection of Hydrogen Peroxide in vitro and in vivo Using Peroxalate Chemiluminescent Micelles

Lee, I.; Hwang, O.; Yoo, D.; Khang, G.; Lee, D., 2011; Vol. 32.

Reduction of oxidative stress by p-hydroxybenzyl alcohol-containing biodegradable polyoxalate nanoparticulate antioxidant

Kim, S.; Park, H.; Song, Y.; Hong, D.; Kim, O.; Jo, E.; Khang, G.; Lee, D., 2011; Vol. 32, p 3021-9.

Reduced inflammatory responses to poly(lactic-co-glycolic acid) by the incorporation of hydroxybenzyl alcohol releasing polyoxalate

Kim, S.; Lee, Y.; Park, H.; Hong, D.; Khang, G.; Lee, D., 2011; Vol. 19.

Biodegradable polyoxalate and copolyoxalate particles for drug-delivery applications

Hong, D.; Song, B.; Kim, H.; Kwon, J.; Khang, G.; Lee, D., 2011; Vol. 2, p 1407-17.

Antioxidant and Anti-Inflammatory Activities of Hydroxybenzyl Alcohol Releasing Biodegradable Polyoxalate Nanoparticles

Park, H.; Kim, S.; Kim, S.; Song, Y.; Seung, K.; Hong, D.; Khang, G.; Lee, D., 2010; Vol. 11, p 2103-8.

Polyoxalate Nanoparticles as a Biodegradable and Biocompatible Drug Delivery Vehicle

Kim, S.; Seong, K.; Kim, O.; Kim, S.; Seo, H.; Lee, M.; Khang, G.; Lee, D., 2010; Vol. 11, p 555-60.